KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TKTL2
All Species:
23.03
Human Site:
S552
Identified Species:
46.06
UniProt:
Q9H0I9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0I9
NP_115512.3
626
67877
S552
D
A
A
T
I
I
S
S
A
K
A
T
G
G
R
Chimpanzee
Pan troglodytes
Q5R1W6
623
67821
S548
D
R
K
L
I
L
D
S
A
R
A
T
K
G
R
Rhesus Macaque
Macaca mulatta
XP_001095403
703
76522
S629
D
A
A
T
I
I
S
S
A
K
A
T
G
G
R
Dog
Lupus familis
XP_538204
596
64805
N522
D
V
T
T
I
I
S
N
A
K
A
T
G
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4D4
627
68429
S553
D
A
V
T
I
I
Q
S
A
K
A
T
G
G
Q
Rat
Rattus norvegicus
P50137
623
67625
C548
D
K
K
L
I
L
D
C
A
R
A
T
K
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508404
725
77819
S650
D
K
K
L
I
L
D
S
A
K
A
T
K
G
R
Chicken
Gallus gallus
XP_414333
627
68436
N548
D
K
K
T
I
L
E
N
A
R
A
T
K
G
R
Frog
Xenopus laevis
NP_001079885
625
67433
S551
D
A
A
T
I
L
S
S
G
R
A
T
G
G
H
Zebra Danio
Brachydanio rerio
NP_932336
625
67820
S551
D
A
S
T
I
V
A
S
A
R
A
T
G
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623357
627
67899
N553
D
A
Q
L
I
V
K
N
A
K
E
V
G
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23254
680
73787
R602
D
K
Q
P
L
E
Y
R
L
S
V
L
P
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.1
85.9
75.4
N.A.
80.5
66.1
N.A.
56.8
66.5
72
69.3
N.A.
N.A.
60.1
N.A.
N.A.
Protein Similarity:
100
79.5
86.7
83
N.A.
89.4
79.5
N.A.
69
80.5
84.8
83.3
N.A.
N.A.
75.5
N.A.
N.A.
P-Site Identity:
100
53.3
100
80
N.A.
80
46.6
N.A.
60
53.3
73.3
73.3
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
100
66.6
100
86.6
N.A.
86.6
60
N.A.
66.6
73.3
86.6
100
N.A.
N.A.
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
25
0
0
0
9
0
84
0
84
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
25
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
9
9
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
59
92
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
92
34
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
34
34
0
0
0
9
0
0
50
0
0
34
0
0
% K
% Leu:
0
0
0
34
9
42
0
0
9
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
17
0
0
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
0
0
0
9
0
42
0
0
0
0
75
% R
% Ser:
0
0
9
0
0
0
34
59
0
9
0
0
0
0
0
% S
% Thr:
0
0
9
59
0
0
0
0
0
0
0
84
0
0
0
% T
% Val:
0
9
9
0
0
17
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _